Unwritten history is not easy to interpret, and, although much may be learned from a study of the drawings, bony remains, and surgical tools of early humans, it is difficult to reconstruct their mental attitude toward the problems of disease and death. It seems probable that, as soon as they reached the stage of reasoning, they discovered by the process of trial and error which plants might be used as foods, which of them were poisonous, and which of them had some medicinal value. Folk medicine or domestic medicine, consisting largely in the use of vegetable products, or herbs, originated in this fashion and still persists.

In this episode, we followed on from last week's Functional Forum and talked about the role of education in the future of medicine, and particularly the role of delivery of content. Danny introduces us to a great resource for practitioners who are interested in creating dynamic content. The book is available for download May 4th through May 8th at goevomed.com/teach. If you're listening to this podcast between May 4th and May 8th, go get it right now. We had a great half-an-hour discussion. Send us your thoughts and feedback!
Founder and currently Executive Editor of Science-Based Medicine Steven Novella, MD is an academic clinical neurologist at the Yale University School of Medicine. He is also the host and producer of the popular weekly science podcast, The Skeptics’ Guide to the Universe, and the author of the NeuroLogicaBlog, a daily blog that covers news and issues in neuroscience, but also general science, scientific skepticism, philosophy of science, critical thinking, and the intersection of science with the media and society. Dr. Novella also has produced two courses with The Great Courses, and published a book on critical thinking - also called The Skeptics Guide to the Universe.
She is the co-founder of the American Holistic Medical Association, as well as the co-founder of the Academy of Parapsychology and Medicine. Dr. Gladys shares her experience from medical school in the 1940's during a war to now and how medicine has changed from treating the disease to treating the person. Dr. Galdys talks the talk and she definitely walks the walk. She's a prime example of what we're trying to accomplish with our Journey to 100 project. Journey To 100 is a world-exclusive conference that will explore options for a sustainable approach to healthcare and longevity and begin Guernsey’s quest to become the first country with a life expectancy of 100. 

The first medical schools were opened in the 9th century, most notably the Schola Medica Salernitana at Salerno in southern Italy. The cosmopolitan influences from Greek, Latin, Arabic, and Hebrew sources gave it an international reputation as the Hippocratic City. Students from wealthy families came for three years of preliminary studies and five of medical studies. The medicine, following the laws of Federico II, that he founded in 1224 the University ad improved the Schola Salernitana, in the period between 1200 and 1400, it had in Sicily (so-called Sicilian Middle Ages) a particular development so much to create a true school of Jewish medicine.[73]

Two great Alexandrians laid the foundations for the scientific study of anatomy and physiology, Herophilus of Chalcedon and Erasistratus of Ceos.[48] Other Alexandrian surgeons gave us ligature (hemostasis), lithotomy, hernia operations, ophthalmic surgery, plastic surgery, methods of reduction of dislocations and fractures, tracheotomy, and mandrake as an anaesthetic. Some of what we know of them comes from Celsus and Galen of Pergamum.[49]
^ Nesse RM, Bergstrom CT, Ellison PT, Flier JS, Gluckman P, Govindaraju DR, Niethammer D, Omenn GS, Perlman RL, Schwartz MD, Thomas MG, Stearns SC, Valle D (January 2010). "Evolution in health and medicine Sackler colloquium: Making evolutionary biology a basic science for medicine". Proceedings of the National Academy of Sciences of the United States of America. 107. 107 Suppl 1 (suppl_1): 1800–7. doi:10.1073/pnas.0906224106. PMC 2868284. PMID 19918069.
During the 16th century there were some improvements in medicine. However it remained basically the same as in the Middle Ages. Medicine was still dominated by the theory of the four humors. In 1546 a man Girolamo Fracastoro published a book called On Contagion. He suggested that infectious diseases were caused by 'disease seeds', which were carried by the wind or transmitted by touch. Unfortunately there was no way of testing his theory.
By the thirteenth century, the medical school at Montpellier began to eclipse the Salernitan school. In the 12th century, universities were founded in Italy, France, and England, which soon developed schools of medicine. The University of Montpellier in France and Italy's University of Padua and University of Bologna were leading schools. Nearly all the learning was from lectures and readings in Hippocrates, Galen, Avicenna, and Aristotle.

Maintaining a comfortable state of health is a goal shared by much of the world’s population past and present, thus the history of health and medicine weaves a thread connecting us with our ancestors’ human experiences. Yet it’s easy to assume that studying it involves either celebrating the ‘eureka moments’ of well-known heroes or laughing at outdated therapies. But, as I set out to show in my book, The History of Medicine in 100 Facts (Amberley Publishing, 2015), medicine’s past features plenty of lesser-known but equally fascinating episodes…
Contrary to what might be expected, the widespread practice of embalming the dead body did not stimulate study of human anatomy. The preservation of mummies has, however, revealed some of the diseases suffered at that time, including arthritis, tuberculosis of the bone, gout, tooth decay, bladder stones, and gallstones; there is evidence too of the parasitic disease schistosomiasis, which remains a scourge still. There seems to have been no syphilis or rickets.

After AD 400, the study and practice of medicine in the Western Roman Empire went into deep decline. Medical services were provided, especially for the poor, in the thousands of monastic hospitals that sprang up across Europe, but the care was rudimentary and mainly palliative.[69] Most of the writings of Galen and Hippocrates were lost to the West, with the summaries and compendia of St. Isidore of Seville being the primary channel for transmitting Greek medical ideas.[70] The Carolingian renaissance brought increased contact with Byzantium and a greater awareness of ancient medicine,[71] but only with the twelfth-century renaissance and the new translations coming from Muslim and Jewish sources in Spain, and the fifteenth-century flood of resources after the fall of Constantinople did the West fully recover its acquaintance with classical antiquity.
Women had always served in ancillary roles, and as midwives and healers. The professionalization of medicine forced them increasingly to the sidelines. As hospitals multiplied they relied in Europe on orders of Roman Catholic nun-nurses, and German Protestant and Anglican deaconesses in the early 19th century. They were trained in traditional methods of physical care that involved little knowledge of medicine. The breakthrough to professionalization based on knowledge of advanced medicine was led by Florence Nightingale in England. She resolved to provide more advanced training than she saw on the Continent. At Kaiserswerth, where the first German nursing schools were founded in 1836 by Theodor Fliedner, she said, "The nursing was nil and the hygiene horrible."[119]) Britain's male doctors preferred the old system, but Nightingale won out and her Nightingale Training School opened in 1860 and became a model. The Nightingale solution depended on the patronage of upper class women, and they proved eager to serve. Royalty became involved. In 1902 the wife of the British king took control of the nursing unit of the British army, became its president, and renamed it after herself as the Queen Alexandra's Royal Army Nursing Corps; when she died the next queen became president. Today its Colonel In Chief is Sophie, Countess of Wessex, the daughter-in-law of Queen Elizabeth II. In the United States, upper middle class women who already supported hospitals promoted nursing. The new profession proved highly attractive to women of all backgrounds, and schools of nursing opened in the late 19th century. They soon a function of large hospitals, where they provided a steady stream of low-paid idealistic workers. The International Red Cross began operations in numerous countries in the late 19th century, promoting nursing as an ideal profession for middle class women.[120]
In the 1830s in Italy, Agostino Bassi traced the silkworm disease muscardine to microorganisms. Meanwhile, in Germany, Theodor Schwann led research on alcoholic fermentation by yeast, proposing that living microorganisms were responsible. Leading chemists, such as Justus von Liebig, seeking solely physicochemical explanations, derided this claim and alleged that Schwann was regressing to vitalism.
This is a security feature. Do not change this feature unless the scope of the change is fully understood. You should take a network trace before changing this value to confirm that the request is not malicious. If double escape sequences are allowed by the server, modify the configuration/system.webServer/security/requestFiltering@allowDoubleEscaping setting. This could be caused by a malformed URL sent to the server by a malicious user.
We've brought her back because her practice is now a huge success.  She's implemented many of the things that we speak about in the 60 Day Practice Accelerator program and the Functional Forum.  James, as a member of her practice, has witnessed it firsthand.  Dr. Berzin is now opening more practices and looking for more physicians to bring on board.

All the way through the Functional Forum and the Evolution of Medicine we've sighted the future of "primary care" to be enhanced through technology, the Functional Medicine operating systems, and coaching for behavior change and this is such a great example. One of the powerful tools that Powell has taken advantage is Nudge Coach, a behavior change technology we love. By taking advantage of their white label solution, they have a branded experience for their patients to use to track behavior change between visits.
In 1954 Joseph Murray, J. Hartwell Harrison and others accomplished the first kidney transplantation. Transplantations of other organs, such as heart, liver and pancreas, were also introduced during the later 20th century. The first partial face transplant was performed in 2005, and the first full one in 2010. By the end of the 20th century, microtechnology had been used to create tiny robotic devices to assist microsurgery using micro-video and fiber-optic cameras to view internal tissues during surgery with minimally invasive practices.[180]
James Maskell:  Yeah.  Well, obviously, you have, some of the ideas you talked about there are perfect I think. I just wrote a blog for The ZocDoc Blog about why doctors should curate their patient education.  And curating resources is much more efficient than just telling people stuff.  You don’t need people to do that, you just need to use the resources that are available.  And so actually, one of the ways that we designed this summit was that it would be almost like the perfect thing for a doctor to curate for their patient—because there is a patient track.  It’s going to basically teach the patient how to be a great patient and how to look after the four major modifiable causes of chronic disease: diet and stress, toxicity, immunity, and the microbiome.  These are all things that patients have the majority of control over.  This is not medicine that’s done to you.  And so, we were just—so that’s part of the track in the doctor track.  I think the curation of patient education can take a lot of the time out of the appointments, because you see one of the biggest things about functional medicine is that it takes a lot of time to do it, because you have to listen and so forth.  So that’s one of the things.  But like you said, technology can play a key role.  And we have doctors in the summit that are talking about how they’re using technology even in poorer, rural areas of the country, where they’re building community-orientated practices that serve a blue-collar type of patient, and it’s working.  And if it could work in rural Indiana, it can work anywhere.  And that’s really exciting.  You know, our vision for this, Chris, is just a nationwide network of remarkable community-orientated functional practices.  In the same ways you saw the natural response to Walmart was farmers’ markets—you know, going directly to the farmer and having that direct interaction—I think the natural reaction to big medicine is these small micropractices that deliver exceptional value to patients in local areas into the community.
Over the centuries, reports occasionally surfaced of caesarean sections saving the lives of both mother and baby, but even after the introduction of antiseptic methods and anaesthesia, caesareans remained a dangerous last resort. So Edinburgh surgeons were surprised to hear a lecture by Robert Felkin, a missionary doctor, about a successful operation that he had witnessed in the African kingdom of Bunyoro Kitara five years earlier.
Leeches had advantages over the common practice of bloodletting using a lancet – the loss of blood was more gradual and less of a shock for those of delicate constitution. And because Broussais’s followers used leeches in place of all the other medicines at the 19th-century physician’s disposal, patients were spared some harsh remedies that might otherwise have made them feel worse. In 1822, a British surgeon called Rees Price coined the term sangui-suction for leech therapy.
We've brought her back because her practice is now a huge success.  She's implemented many of the things that we speak about in the 60 Day Practice Accelerator program and the Functional Forum.  James, as a member of her practice, has witnessed it firsthand.  Dr. Berzin is now opening more practices and looking for more physicians to bring on board.

The paper of Paul Ewald in 1980, “Evolutionary Biology and the Treatment of Signs and Symptoms of Infectious Disease”,[79] and that of Williams and Nesse in 1991, “The Dawn of Darwinian Medicine”[15] were key developments. The latter paper “draw a favorable reception”,[43]page x and led to a book, Why We Get Sick (published as Evolution and healing in the UK). In 2008, an online journal started: Evolution and Medicine Review.
In 1847 in Vienna, Ignaz Semmelweis (1818–1865), dramatically reduced the death rate of new mothers (due to childbed fever) by requiring physicians to clean their hands before attending childbirth, yet his principles were marginalized and attacked by professional peers.[115] At that time most people still believed that infections were caused by foul odors called miasmas.

In London, the crown allowed two hospitals to continue their charitable work, under nonreligious control of city officials.[96] The convents were all shut down but Harkness finds that women—some of them former nuns—were part of a new system that delivered essential medical services to people outside their family. They were employed by parishes and hospitals, as well as by private families, and provided nursing care as well as some medical, pharmaceutical, and surgical services.[97]
^ Cooter, R.J. (1976). "Phrenology and British alienists, c. 1825–1845. Part I: Converts to a doctrine". Medical History. 20 (1): 1–21. doi:10.1017/s0025727300021761. PMC 1081688. PMID 765647.; Cooter, R.J. (1976). "Phrenology and British alienists, c. 1825–1845. Part II: Doctrine and practice". Medical History. 20 (2): 135–51. doi:10.1017/s0025727300022195. PMC 1081733. PMID 781421.
Magic and religion played a large part in the medicine of prehistoric or early human society. Administration of a vegetable drug or remedy by mouth was accompanied by incantations, dancing, grimaces, and all the tricks of the magician. Therefore, the first doctors, or “medicine men,” were witch doctors or sorcerers. The use of charms and talismans, still prevalent in modern times, is of ancient origin.

During the 18th century superstition declined. In 1700 many people believed that scrofula (a form of tubercular infection) could be healed by a monarch's touch. (Scrofula was called the kings evil). Queen Anne (reigned 1702-1714) was the last British monarch to touch for scrofula. Despite the decline of superstition there were still many quacks in the 18th century. Limited medical knowledge meant many people were desperate for a cure. One of the most common treatments, for the wealthy, was bathing in or drinking spa water, which they believed could cure all kinds of illness.
By the thirteenth century, the medical school at Montpellier began to eclipse the Salernitan school. In the 12th century, universities were founded in Italy, France, and England, which soon developed schools of medicine. The University of Montpellier in France and Italy's University of Padua and University of Bologna were leading schools. Nearly all the learning was from lectures and readings in Hippocrates, Galen, Avicenna, and Aristotle.
Chris Kresser:  Yeah, sure.  I’m sure a lot of my listeners know this about me, but for those people who are new to this especially, I think Paleo—and I’ve said this before—is a fantastic starting place, but it’s not a destination.  What I mean by that, is we know that Paleo foods are safe and well tolerated for most of us because we’ve eaten them for such a long period of time.  And by we, I mean human beings.  And they’re the least likely to cause problems, allergies, food intolerances, and issues like that, because human beings have been consuming them for thousands of generations.  But that doesn’t mean that we absolutely need to restrict our diet to those foods, because even though we’re largely the same genetically as we were 10,000 years ago, there have been significant changes.  In fact, as much as 10% of our genome shows evidence of recent selection.  And the pace of genetic change today is occurring at a rate 100 times faster than the average over 6 million years of hominid evolution.  So we’re similar to our Paleolithic ancestors, but we’re different in some important ways.  And those differences actually do affect our tolerance of certain agricultural foods, like full-fat and fermented dairy products, even legumes and grains, some of the newly introduced foods like alcohol and chocolate and coffee.  These are all foods that modern research actually suggests can be beneficial when they are well tolerated, but I call them gray-area foods because our tolerance of them really depends on the individual.  So for one person who is casein intolerant or intolerant to some of the proteins in dairy, eating any dairy is going to be problematic.  But for someone who has no problem with casein or lactose, the sugar in dairy, all of the research on full-fat dairy suggests that it’s beneficial and may reduce the risk of cardiovascular and metabolic disease, and even obesity.  So those are just a few examples of how our diet has changed.  And I think as a healthcare practitioner, my focus is always on the science—what the science shows, and what I see in the clinic in my work with patients.  And I’m generally kind of allergic to extremely rigid, dogmatic approaches, especially when they’re not flexible enough to evolve and adapt with what the changing science tells us.  So that was one of the big focuses of my talk at the summit.
China also developed a large body of traditional medicine. Much of the philosophy of traditional Chinese medicine derived from empirical observations of disease and illness by Taoist physicians and reflects the classical Chinese belief that individual human experiences express causative principles effective in the environment at all scales. These causative principles, whether material, essential, or mystical, correlate as the expression of the natural order of the universe.
^ Jump up to: a b Askitopoulou, H.; Konsolaki, E.; Ramoutsaki, I.; Anastassaki, E. (2002). Surgical cures by sleep induction as the Asclepieion of Epidaurus. The history of anesthesia: proceedings of the Fifth International Symposium, by José Carlos Diz, Avelino Franco, Douglas R. Bacon, J. Rupreht, Julián Alvarez. Elsevier Science B.V., International Congress Series 1242. pp. 11–17. ISBN 978-0444512932.
After the atomic bombing at the end of World War II, anxieties about survival in the nuclear age led scientists to begin stockpiling and freezing hundreds of thousands of blood samples from indigenous communities around the world. These samples were believed to embody potentially invaluable biological information about genetic ancestry, evolution, microbes, and much more. In Life on Ice, Joanna Radin examines how and why these frozen blood samples shaped the practice known as biobanking.
510-430 BC - Alcmaeon of Croton scientific anatomic dissections. He studied the optic nerves and the brain, arguing that the brain was the seat of the senses and intelligence. He distinguished veins from the arteries and had at least vague understanding of the circulation of the blood.[2] Variously described by modern scholars as Father of Anatomy; Father of Physiology; Father of Embryology; Father of Psychology; Creator of Psychiatry; Founder of Gynecology; and as the Father of Medicine itself.[6] There is little evidence to support the claims but he is, nonetheless, important.[5][7]
The Program in the History of Medicine at Cedars-Sinai explores the body and its cultural contexts from the early modern period to the present. The program’s faculty covers a range of subdisciplines, including visual culture, gender, history of the book and historical epistemology. A commitment to scholarly rigor and interdisciplinary experiment, as well as an ecumenical embrace of a wide variety of historical methods and evidence guide the program’s original scholarship.
On June 1, 2018 a symposium, 100 Years of Women at Yale School of Medicine, commemorated the 100-year anniversary of women at YSM. This daylong event, open to all faculty, students, staff, alumni, and clinicians in the community, was sponsored by the Committee on the Status of Women in Medicine (SWIM), the Minority Organization for Retention & Expansion (MORE), and the Dean’s Office.  This event celebrated the contributions of women faculty and alumni from the School of Medicine. The symposium featured speakers, including Naomi Rogers, PhD, Professor in the History of Medicine and of History who discussed the challenges for women in their fields, as well as those encountered on the pathway to finding work-life balance. 
Medicine made huge advances in the 20th century. The first non-direct blood transfusion was made in 1914. Insulin was first used to treat a patient in 1922. The EEG machine was first used in 1929. Meanwhile many new drugs were developed. In 1910 the discovered salvarsan, a drug used to treat syphilis was discovered. In 1935 prontosil was used to treat blood poisoning. Later it was discovered that the active ingredient of the dye was a chemical called sulphonamide, which was derived from coal tar. As a result in the late 1930s a range of drugs derived from sulphonamide were developed.

^ Hayward, Rhodri (2011). "Medicine and the Mind". In Jackson, Mark. The Oxford Handbook of the History of Medicine. Oxford University Press. pp. 524–42. ISBN 978-0199546497.; Scull, Andrew (2005). Most Solitary of Afflictions: Madness And Society in Britain, 1700–1900. Yale University Press. pp. 324–28. ISBN 978-0300107548.; Dowbiggin, I. (1992). ""An exodus of enthusiasm": G. Alder Blumer, eugenics, and US psychiatry, 1890–1920". Medical History. 36 (4): 379–402. doi:10.1017/S002572730005568X. PMC 1036631. PMID 1435019.; Snelders, S.; Meijman, F.J.; Pieters, T. (2007). "Heredity and alcoholism in the medical sphere: The Netherlands, 1850–1900". Medical History. 51 (2): 219–36. doi:10.1017/S0025727300001204. PMC 1871693. PMID 17538696.; Turda, M. (2009). ""To end the degeneration of a nation": Debates on eugenic sterilization in inter-war Romania". Medical History. 53 (1): 77–104. doi:10.1017/S002572730000332X. PMC 2629178. PMID 19190750.
This week on the Evolution of Medicine podcast continues our “Success Leaves Clues” series, “From Matrix to Action” and welcome former Functional Forum guest Dr. Lara Salyer of Health Innate. Dr. Salyer, DO was featured on the Functional Forum this year, is an enthusiastic member of our Practice Accelerator program, and runs a functional medicine practice in rural Wisconsin.