James Maskell:  Absolutely.  The evolutionary concepts were one of the big reasons why I wanted you to be in there, Chris, because I know you do the Paleo, which is evolutionary in itself.  But also, one of the things that you talk about is how the Paleo diet is something that has needed to change and evolve, and how we’ve evolved to go beyond what our ancestors ate.  I don’t know, maybe for your listeners, they might be interested to just get a snapshot of that.  Because that’s one of the cool things in nutrition that I think that you bring together, is a very sensible approach to eating. I thought that was one of the highlights for the nutrition part of the summit.
This week on the Evolution of Medicine podcast, we welcome Gladys McGarey. At 97 years old, Galdys is a true pioneer in holistic and living medicine and we're absolutely thrilled to welcome her to the podcast. Dr. Gladys is internationally recognized as the Mother of Holistic Medicine.  Dr. Gladys, as she is affectionately known, is board certified in Holistic and Integrated Medicine and has held a family practice for more than sixty years.  
This week on the Evolution of Medicine podcast, we welcome Brian Mulvaney, Director of Strategy at CrossFit. If you’ve been part of our community for awhile, you know that we’re working towards helping create 100k micropractices. Our plan for micropractices very much mirrors the Crossfit strategy – reduce the overhead, empower individuals to become entrepreneurs.
Byzantine physicians often compiled and standardized medical knowledge into textbooks. Their records tended to include both diagnostic explanations and technical drawings. The Medical Compendium in Seven Books, written by the leading physician Paul of Aegina, survived as a particularly thorough source of medical knowledge. This compendium, written in the late seventh century, remained in use as a standard textbook for the following 800 years.
3 Schwarz, Richard W. “John Harvey Kellogg, M.D.: Pioneering Health Reformer.” John Harvery Kellogg, M.D.: Pioneering Health Reformer – Richard W. Schwarz – Google Books. Google Books, 2006. Web. 26 Jan. 2014. .
In Britain, there were but three small hospitals after 1550. Pelling and Webster estimate that in London in the 1580 to 1600 period, out of a population of nearly 200,000 people, there were about 500 medical practitioners. Nurses and midwives are not included. There were about 50 physicians, 100 licensed surgeons, 100 apothecaries, and 250 additional unlicensed practitioners. In the last category about 25% were women.[101] All across Britain—and indeed all of the world—the vast majority of the people in city, town or countryside depended for medical care on local amateurs with no professional training but with a reputation as wise healers who could diagnose problems and advise sick people what to do—and perhaps set broken bones, pull a tooth, give some traditional herbs or brews or perform a little magic to cure what ailed them.
This week on the Evolution of Medicine podcast,  we hear from Richard Morris, CEO of Powell Metabolics. Powell Metabolics is an innovative wellness coaching program delivered in a physical therapy environment that started in Arizona and has the potential to expand across the country. This is part of a greater trend of functional medicine integrating with other "hands on" modalities like physical therapy, personal training and chiropractic. We think you'll be inspired to hear about their process, the results and how your practice could benefit.
This week on the Evolution of Medicine podcast we welcome the Mark Krasser and Anna Gannon from Expectful. Expectful provides guided meditation for fertility, pregnancy, and motherhood. At the Evolution of Medicine, we often talk about the power of digital health and how it comes together with medicine to solve chronic disease. Mark and Anna join us to explain the science behind how meditation can support mom during pregnancy and labor. They also explain the deeper bond mom and baby feel, as well as, how it supports baby's health.

1950s: A series of successful anti-psychotic drugs are introduced that do not cure psychosis but control its symptoms. The first of the anti-psychotics, the major class of drug used to treat psychosis, is discovered in France in 1952 and is named chlorpromazine (Thorazine). Studies show that 70 percent of patients with schizophrenia clearly improve on anti-psychotic drugs.
Wes starts by sharing his own story of abuse and his journey to starting A Human Project. As he started to understand his own gut-brain connection and effects of the medications that were supposed to be helping him, he decided to take his life into his own hands. Now he focuses on helping children through things like stress, bullying and suicidal thoughts. We hope that this podcast inspires you as much as it has inspired us. Please consider supporting this very worthy cause at A Human Project.
She is the co-founder of the American Holistic Medical Association, as well as the co-founder of the Academy of Parapsychology and Medicine. Dr. Gladys shares her experience from medical school in the 1940's during a war to now and how medicine has changed from treating the disease to treating the person. Dr. Galdys talks the talk and she definitely walks the walk. She's a prime example of what we're trying to accomplish with our Journey to 100 project. Journey To 100 is a world-exclusive conference that will explore options for a sustainable approach to healthcare and longevity and begin Guernsey’s quest to become the first country with a life expectancy of 100. 
A leading journal in its field for more than three quarters of a century, the Bulletin spans the social, cultural, and scientific aspects of the history of medicine worldwide. Every issue includes reviews of recent books on medical history. Recurring sections include Digital Media & Humanities and Pedagogy. Bulletin of the History of Medicine is the official publication of the American Association for the History of Medicine (AAHM) and the Johns Hopkins Institute of the History of Medicine.
During the Renaissance, understanding of anatomy improved, and the microscope was invented. Prior to the 19th century, humorism (also known as humoralism) was thought to explain the cause of disease but it was gradually replaced by the germ theory of disease, leading to effective treatments and even cures for many infectious diseases. Military doctors advanced the methods of trauma treatment and surgery. Public health measures were developed especially in the 19th century as the rapid growth of cities required systematic sanitary measures. Advanced research centers opened in the early 20th century, often connected with major hospitals. The mid-20th century was characterized by new biological treatments, such as antibiotics. These advancements, along with developments in chemistry, genetics, and radiography led to modern medicine. Medicine was heavily professionalized in the 20th century, and new careers opened to women as nurses (from the 1870s) and as physicians (especially after 1970).
The sexual revolution included taboo-breaking research in human sexuality such as the 1948 and 1953 Kinsey reports, invention of hormonal contraception, and the normalization of abortion and homosexuality in many countries. Family planning has promoted a demographic transition in most of the world. With threatening sexually transmitted infections, not least HIV, use of barrier contraception has become imperative. The struggle against HIV has improved antiretroviral treatments.
In this review, the endlessness evolution of medical science and medical technology, and its effects on disease metamorphosis and increased life expectancy are discussed. In certain instances, the past will be compared with the present and predictions for the future will be outlined. Further, the constant role of the physician in maintaining the health of human beings is emphasized in this endlessness evolution.
Retinal neurons and their axon output have evolved to be inside the layer of retinal pigment cells. This creates a constraint on the evolution of the visual system such that the optic nerve is forced to exit the retina through a point called the optic disc. This, in turn, creates a blind spot. More importantly, it makes vision vulnerable to increased pressure within the eye (glaucoma) since this cups and damages the optic nerve at this point, resulting in impaired vision.
Furthermore during the 18th century a number of hospitals were founded. In 1724 Guys Hospital was founded with a bequest from a merchant named Thomas Guy. St Georges was founded in 1733 and Middlesex Hospital in 1745. Hospitals were also founded in Bristol in 1733, York in 1740, Exeter in 1741 and Liverpool in 1745. The first civilian hospital in America opened in Philadelphia in 1751. In the late 18th century and early 19th century dispensaries were founded in many towns. They were charities were the poor could obtain free medicines.
Guy's Hospital, the first great British hospital opened in 1721 in London, with funding from businessman Thomas Guy. In 1821 a bequest of £200,000 by William Hunt in 1829 funded expansion for an additional hundred beds. Samuel Sharp (1709–78), a surgeon at Guy's Hospital, from 1733 to 1757, was internationally famous; his A Treatise on the Operations of Surgery (1st ed., 1739), was the first British study focused exclusively on operative technique.[103]
1656 Experimenting on dogs, English architect Sir Christopher Wren is the first to administer medications intravenously by means of an animal bladder attached to a sharpened quill. Wren also experiments with canine blood transfusions (although safe human blood transfusions only became feasible after Karl Landsteiner develops the ABO blood-typing system in 1900).
^ Porter, Roy (1999). The Greatest Benefit to Mankind: A Medical History of Humanity from Antiquity to the Present. London: Fontana. p. 493. ISBN 978-0393319804.; Porter, Roy (1992). "Madness and its Institutions". In Wear, Andrew. Medicine in Society: Historical Essays. Cambridge: Cambridge University Press. pp. 277–302. ISBN 978-0521336390.; Suzuki, A. (1991). "Lunacy in seventeenth- and eighteenth-century England: Analysis of Quarter Sessions records Part I". History of Psychiatry. 2 (8): 437–56. doi:10.1177/0957154X9100200807. PMID 11612606.; Suzuki, A. (1992). "Lunacy in seventeenth- and eighteenth-century England: Analysis of Quarter Sessions records Part II". History of Psychiatry. 3 (9): 29–44. doi:10.1177/0957154X9200300903. PMID 11612665.

Sushruta advises his students that however well read they are, they are not competent to treat disease until they have practical experience. Surgical incisions were to be tried out on the skin of fruits, while carefully extracting fruit seeds enabled the student to develop the skill of removing foreign bodies from flesh. They also practised on dead animals and on leather bags filled with water, before being let loose on real patients.
Trapped in ice near Stadacona (the site of present-day Quebec City) in 1536, Jacques Cartier’s ships weren’t going anywhere. The crews, holed up in a makeshift fort with little access to fresh food, came down with a disease so gruesome that “their mouth became stincking, their gummes so rotten, that all the flesh did fall off, even to the rootes of the teeth, which did also almost all fall out.” They had scurvy, now known to result from a deficiency of vitamin C. Cartier had no idea what to do.

^ Houstoun, Robert; Cheselden, William; Arbuthnot, John (1723). Lithotomus castratus; or Mr. Cheselden's Treatise on the high operation for the stone: thoroughly examin'd and plainly found to be Lithotomia Douglassiana, under another title: in a letter to Dr. John Arbuthnot. With an appendix, wherein both authors are fairly compar'd. T. Payne. Retrieved 7 December 2012.
James Maskell:  Yeah, absolutely, it was great.  You know, we have a whole day based on the evolution of nutrition.  It includes you and Terry Wahls, talking about the nutrition side.  But we also have Food Babe in there because she’s not really in the Paleo world, but I think a big part of the evolution of nutrition is to really get active and find out what’s in the food.  And I really commend her.  I think she’s playing a big role in sort of holding some of these food companies accountable.  And I think activism is an important part of making sure that we do have good options in the future.  So she’s included on that day.  And then Darryl Edwards, who does his Primal Play. He’s just a great guy, another English guy.  He’s going to be talking about the evolution of exercise.  I had an opportunity to do one of his Primal Play sessions in Central Park.  And I can tell you, I was hurting the next day and the day after, in places that I didn’t realize I had muscles.
In 1847 in Vienna, Ignaz Semmelweis (1818–1865), dramatically reduced the death rate of new mothers (due to childbed fever) by requiring physicians to clean their hands before attending childbirth, yet his principles were marginalized and attacked by professional peers.[115] At that time most people still believed that infections were caused by foul odors called miasmas.
1901 Austrian-American Karl Landsteiner describes blood compatibility and rejection (i.e., what happens when a person receives a blood transfusion from another human of either compatible or incompatible blood type), developing the ABO system of blood typing. This system classifies the bloods of human beings into A, B, AB, and O groups. Landsteiner receives the 1930 Nobel Prize for Physiology or Medicine for this discovery.
Seishu Hanaoka (1760–1835) studied medicine in Kyoto and set up a practice in his hometown of Hirayama. He became interested in the idea of anaesthesia owing to stories that a third-century Chinese surgeon Houa T’o had developed a compound drug enabling patients to sleep through the pain. Hanaoka experimented with similar formulae and produced Tsusensan, a potent hot drink. Among other botanical ingredients it contained the plants Datura metel (aka Datura alba or ‘devil’s trumpet’), monkshood and Angelica decursiva, all of which contain some potent physiologically active substances.
Humans evolved to live as simple hunter-gatherers in small tribal bands. Contemporary humans now have a very different environment and way of life.[13][14] This change makes present humans vulnerable to a number of health problems, termed "diseases of civilization" and "diseases of affluence". Stone-age humans evolved to live off the land, taking advantage of the resources that were readily available to them. Evolution is slow, and the rapid change from stone-age environments and practices to the world of today is problematic because we are still adapted to stone-age circumstances that no longer apply. This misfit has serious implications for our health. "Modern environments may cause many diseases such as deficiency syndromes like scurvy and rickets".[15])

Chris Kresser:  Yeah, that’s pretty amazing.  I talked with Mark Hyman a little bit about the Cleveland Clinic Functional Medicine Program.  And just for the listeners, what this is—and James, you might know a little bit more about it than I do—but just from what Mark said, the Cleveland Clinic, for those who don’t know, is a major institution in the field of medical research and pioneering new treatments and approaches to disease from the more mainstream perspective.  They basically invited Mark Hyman to create a functional medicine group within the Cleveland Clinic that is funded and actively looking for strategies. Basically, how to scale functional medicine and make it more viable within the healthcare model that we have.  And that is a really much-needed step because, as I’m sure all the listeners know, right now in functional medicine, everything is paid for out of pocket. Insurance doesn’t cover it.  That really limits the number of people who will be able to take advantage of it.  So getting some mainstream recognition like this for functional medicine is a huge step in terms of making it more accessible and available to the majority of people out there.
When the Roman Empire split into the Western and Eastern Empires, the Western Empire, centered on Rome, went into a deep decline and the art of medicine slowly slipped away, with the physicians becoming pale shadows of their illustrious predecessors and generally causing more harm than good. Western Europe would not appear again in the history of medicine until long after the decline of Islam.

In 1880 Pasteur and a team of coworkers searched for a cure for chicken cholera. Pasteur and his team grew germs in a sterile broth. Pasteur told a coworker to inject chickens with the germ culture. However the man forgot and went on holiday. The germs were left exposed to the air. Finally, when he returned the man injected chickens with the broth. However they did not die. So they were injected with a fresh culture. Still they did not die.
“Rescaling Colonial Life From the Indigenous to the Alien: The Late 20th Century Search for Human Biological Futures,“ follows the reach of colonial practices of natural history through genomics and into outer space. The article centers around biochemist and medical anthropologist Baruch Blumberg, who began his career collecting samples from colonial subjects in Surinam and ended it as head of the NASA program in Astrobiology. Joanna Radin’s history traces entwinements of colonial natural history, space exploration, and inductive methods in postwar biological science.
In spite of early scepticism, theriac took off as a prized (and expensive) cure-all. By the 12th century Venice was the leading exporter and the substance had a high profile in European, Arabic and Chinese medicine alike. Its fortunes waned after 1745, however, when William Heberden debunked its alleged efficacy and suggested that enterprising Romans had exaggerated the Mithradates story for their own gain.

A major breakthrough in epidemiology came with the introduction of statistical maps and graphs. They allowed careful analysis of seasonality issues in disease incidents, and the maps allowed public health officials to identify critical loci for the dissemination of disease. John Snow in London developed the methods. In 1849, he observed that the symptoms of cholera, which had already claimed around 500 lives within a month, were vomiting and diarrhoea. He concluded that the source of contamination must be through ingestion, rather than inhalation as was previously thought. It was this insight that resulted in the removal of The Pump On Broad Street, after which deaths from cholera plummeted afterwards. English nurse Florence Nightingale pioneered analysis of large amounts of statistical data, using graphs and tables, regarding the condition of thousands of patients in the Crimean War to evaluate the efficacy of hospital services. Her methods proved convincing and led to reforms in military and civilian hospitals, usually with the full support of the government.[138][139][140]

In this review, the endlessness evolution of medical science and medical technology, and its effects on disease metamorphosis and increased life expectancy are discussed. In certain instances, the past will be compared with the present and predictions for the future will be outlined. Further, the constant role of the physician in maintaining the health of human beings is emphasized in this endlessness evolution.
The sexual revolution included taboo-breaking research in human sexuality such as the 1948 and 1953 Kinsey reports, invention of hormonal contraception, and the normalization of abortion and homosexuality in many countries. Family planning has promoted a demographic transition in most of the world. With threatening sexually transmitted infections, not least HIV, use of barrier contraception has become imperative. The struggle against HIV has improved antiretroviral treatments.
Last time we featured her, the Evolution of Medicine community showed support and interest that made a real difference. Thank you! We bring her back this week to share an update about Organize.  She and her team were recently at the White House to speak about their project with some important influencers from the industry.  She shares with us what she learned and what they were able to accomplish.
Leeches had advantages over the common practice of bloodletting using a lancet – the loss of blood was more gradual and less of a shock for those of delicate constitution. And because Broussais’s followers used leeches in place of all the other medicines at the 19th-century physician’s disposal, patients were spared some harsh remedies that might otherwise have made them feel worse. In 1822, a British surgeon called Rees Price coined the term sangui-suction for leech therapy.

James pieces together the last twenty five to forty years from the elders of which functional medicine was created. The basis of Functional Medicine is in history of Naturopathic, Chiropractic and Acupuncture along with the nutritional and medical research worlds. The new terminology fits within the paradigm of medicine and allows those in the medical field to grasp the root concepts that have been spoken for the last several hundred to four thousand years. Only now is the science finally catching up to what has been spoken by the elders in those professions.